{"id":3305,"date":"2026-01-14T16:20:35","date_gmt":"2026-01-14T14:20:35","guid":{"rendered":"https:\/\/biostatistics.med.uoa.gr\/?p=3305"},"modified":"2026-01-16T16:21:52","modified_gmt":"2026-01-16T14:21:52","slug":"%cf%80%cf%81%cf%8c%cf%83%ce%ba%ce%bb%ce%b7%cf%83%ce%b7-%cf%83%ce%b5-webinar","status":"publish","type":"post","link":"https:\/\/biostatistics.med.uoa.gr\/en\/%cf%80%cf%81%cf%8c%cf%83%ce%ba%ce%bb%ce%b7%cf%83%ce%b7-%cf%83%ce%b5-webinar\/","title":{"rendered":"\u03a0\u03c1\u03cc\u03c3\u03ba\u03bb\u03b7\u03c3\u03b7 \u03c3\u03b5 webinar"},"content":{"rendered":"<figure class=\"wp-block-table\"><table><tbody><tr><td><strong>Mixed effect models for the spatio-temporal analysis of manifold valued data: application to Alzheimer\u2019s disease screening<\/strong><\/td><\/tr><tr><td><strong>Description<\/strong><strong>:<\/strong> Alzheimer&#8217;s disease (AD) is characterized by the progressive alterations seen in brain images which give rise to the onset of various sets of symptoms. The variability in the dynamics of changes in both brain images and cognitive impairments remains poorly understood. This work introduces AD Course Map a spatiotemporal atlas of Alzheimer&#8217;s disease progression. It summarizes the variability in the progression of a series of neuropsychological assessments, the propagation of hypometabolism and cortical thinning across brain regions and the deformation of the shape of the hippocampus. It also enables to produce also digital twins of individuals to help AD screening. <em>Keywords: digital twin; longitudinal generative statistical model; early diagnostic; Alzheimer\u2019s disease<\/em> &nbsp;<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p><a href=\"https:\/\/www.iscb.org\/glbio2013-program\/glbio2013-poster-presentations\/476-iscbacademy\/4272-iscbacademy-webinars\">https:\/\/www.iscb.org\/glbio2013-program\/glbio2013-poster-presentations\/476-iscbacademy\/4272-iscbacademy-webinars<\/a><\/p>","protected":false},"excerpt":{"rendered":"<p>Mixed effect models for the spatio-temporal analysis of manifold valued data: application to Alzheimer\u2019s disease screening Description: Alzheimer&#8217;s disease (AD) is characterized by the progressive alterations seen in brain images which give rise to the onset of various sets of symptoms. The variability in the dynamics of changes in both brain images and cognitive impairments <a href=\"https:\/\/biostatistics.med.uoa.gr\/en\/%cf%80%cf%81%cf%8c%cf%83%ce%ba%ce%bb%ce%b7%cf%83%ce%b7-%cf%83%ce%b5-webinar\/\" rel=\"nofollow\"><span class=\"sr-only\">Read more about \u03a0\u03c1\u03cc\u03c3\u03ba\u03bb\u03b7\u03c3\u03b7 \u03c3\u03b5 webinar<\/span>[&hellip;]<\/a><\/p>","protected":false},"author":23768,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"_links":{"self":[{"href":"https:\/\/biostatistics.med.uoa.gr\/en\/wp-json\/wp\/v2\/posts\/3305"}],"collection":[{"href":"https:\/\/biostatistics.med.uoa.gr\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/biostatistics.med.uoa.gr\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/biostatistics.med.uoa.gr\/en\/wp-json\/wp\/v2\/users\/23768"}],"replies":[{"embeddable":true,"href":"https:\/\/biostatistics.med.uoa.gr\/en\/wp-json\/wp\/v2\/comments?post=3305"}],"version-history":[{"count":1,"href":"https:\/\/biostatistics.med.uoa.gr\/en\/wp-json\/wp\/v2\/posts\/3305\/revisions"}],"predecessor-version":[{"id":3306,"href":"https:\/\/biostatistics.med.uoa.gr\/en\/wp-json\/wp\/v2\/posts\/3305\/revisions\/3306"}],"wp:attachment":[{"href":"https:\/\/biostatistics.med.uoa.gr\/en\/wp-json\/wp\/v2\/media?parent=3305"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/biostatistics.med.uoa.gr\/en\/wp-json\/wp\/v2\/categories?post=3305"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/biostatistics.med.uoa.gr\/en\/wp-json\/wp\/v2\/tags?post=3305"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}